Company: Change Bio
Founder: Zoe Woods and Noah Sprent
Website: https://www.changebio.uk
About Change Bio
Change Bio was founded in 2023 to solve one of the biggest challenges in sustainable manufacturing: making it easier and more affordable to produce proteins that can replace fossil fuel-based chemicals and animal-derived ingredients. Proteins are nature’s tiny nano-machines. They do everything from digesting food to giving materials their structure. Scientists are now designing new proteins that can break down plastic waste, improve bio-based materials, and create better plant-based foods. However, making these proteins at scale is still too expensive and difficult, which means many never reach the market.
Change Bio solves this by building a next-generation manufacturing platform for proteins. Using precision fermentation, we grow proteins in controlled environments, just like brewing beer but with microbes instead of yeast. Our platform helps companies test, refine, and scale up the production of their proteins quickly and cost-effectively. This allows innovators to bring sustainable proteins to market without needing to build their own expensive manufacturing infrastructure.
Getting here has not been easy. The biggest challenge we have overcome is proving that proteins designed in a lab can be made efficiently at commercial scale. Traditional protein production methods were designed for pharmaceuticals, not materials or food. We had to rethink how proteins are manufactured to make the process flexible, affordable, and sustainable. We developed a system that allows companies to test different versions of a protein before committing to full-scale production. This removes a major risk that has slowed down innovation in the past.
We are still at an early stage, but we have big dreams! We have developed a lab-based proof of concept of our protein manufacturing system and are now expanding to serve our first customers this year.
Our impact will grow as more companies look to proteins as a way to reduce their carbon footprint. Many industrial processes today rely on petrochemicals that take a toll on the environment. By making it easier to manufacture sustainable proteins, we help companies replace carbon-intensive ingredients with bio-based alternatives. For example, a protein that strengthens bio-based plastic could allow manufacturers to reduce their reliance on fossil fuels. A protein that improves the texture of plant-based foods could encourage more people to choose sustainable alternatives to animal products.
Change Bio is not just making proteins. We are building the manufacturing infrastructure needed to scale sustainable solutions across multiple industries. By solving the production bottleneck, we help companies move from discovery to real-world impact. Our goal is to make precision fermentation the go-to method for producing sustainable proteins at scale, unlocking new possibilities for food, materials, and environmental solutions.
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