Top 8 Orthopaedic Startups

Orthopaedics, like most areas of healthcare, is undergoing a remarkable transformation, driven by cutting-edge startups that are redefining how we diagnose, treat and manage musculoskeletal conditions.

From advanced implant technologies to AI-powered rehabilitation solutions, these innovative companies are at the forefront of medical progress, enhancing patient outcomes and improving quality of life.

All around the world, innovative orthopaedic startups are leading the charge, showcasing how they are revolutionising the industry with groundbreaking advancements in surgery, prosthetics, regenerative medicine and more.

 

The Modern Transformation of Orthopedics 

 

Major advancements in orthopaedics are driven by cutting-edge technology that enhances patient outcomes and surgical precision. One major advancement is robotic-assisted surgery which allows for highly accurate joint replacements, reducing recovery times and improving long-term mobility.

3D printing is also transforming the field, enabling the production of custom implants and prosthetics tailored to individual anatomy.

Another breakthrough is regenerative medicine, particularly stem cell therapy and tissue engineering, which hold promise for repairing cartilage and bone damage without invasive surgery. Smart implants, embedded with sensors, provide real-time data on healing progress, allowing clinicians to personalise rehabilitation plans.

In addition, Augmented reality (AR) is also making waves in medicine and ortho in particular, assisting surgeons by overlaying digital models onto real anatomy for enhanced visualisation.

Meanwhile, unsurprisingly, artificial intelligence (AI) is streamlining diagnostics, predicting complications and optimising treatment plans. These innovations are paving the way for more precise, less invasive and highly personalised orthopaedic care.

 

Top 8 Orthopaedic Startups

 

Modern medicine is progressing all over the world, with exciting startups leading the charge in orthopaedic innovation.

Here are eight of the top orthopaedic startups to keep an eye on.

 

ATRI

 

Founded in 2008, ATRI (Advanced Tissue Regeneration Initiative) is revolutionising the orthopaedic industry with cutting-edge regenerative medicine solutions. By leveraging biomaterials and tissue engineering, ATRI is developing next-generation implants and scaffolds designed to enhance bone and soft tissue repair.

This US-based company’s innovations aim to improve healing times, reduce complications and offer more sustainable alternatives to traditional orthopaedic procedures. ATRI’s research-driven approach is paving the way for minimally invasive treatments that promote natural regeneration, benefiting patients and surgeons alike.

 

 

Augmedics

 

 

Augmedics is revolutionising orthopaedic and spinal surgery with its xvision augmented reality (AR) navigation system. Founded in Israel in 2014, this groundbreaking technology enables surgeons to visualise a patient’s internal anatomy in real-time, enhancing precision and reducing the need for traditional fluoroscopy.

By minimising radiation exposure and improving accuracy, Augmedics is making surgical procedures safer and more efficient. With a strong focus on digital surgery and AI-driven navigation, the company continues to push the boundaries of medical innovation.

 

Miach Orthopaedics

 

 

Miach Orthopaedics, founded in the US in 2016, is pioneering biologic solutions for soft tissue repair, with a particular focus on anterior cruciate ligament (ACL) injuries.

Their flagship innovation, the BEAR Implant (Bridge-Enhanced ACL Restoration), offers a graft-free alternative to traditional ACL reconstruction, promoting natural healing by stimulating the body’s own repair mechanisms.

This breakthrough reduces surgical complications, preserves native tissue, and improves long-term knee function. Miach Orthopaedics is redefining sports medicine with its regenerative approach.

 

Proprio

 

 

By means of AI-driven surgical navigation, Proprio is completely transforming orthopaedic surgery. Its Paradigm system combines computer vision, machine learning and real-time imaging to create a highly detailed 3D map of the surgical field, eliminating the need for radiation-based scanning.

This innovation allows surgeons to perform procedures with unparalleled accuracy and efficiency. By merging artificial intelligence with next-generation imaging, Proprio is setting a new standard for precision surgery and digital healthcare.

 

Lazurite

 

 

Founded in 2015, Lazurite is disrupting the field of minimally invasive surgery with its ArthroFree system, the world’s first fully wireless surgical camera.

Designed for the purpose of eliminating cumbersome cables in the operating theatre, this FDA-approved innovation enhances surgeon mobility, reduces contamination risks and streamlines workflow.

Lazurite’s commitment to energy-efficient, wireless technology is setting a new benchmark for arthroscopic and orthopaedic procedures, making surgery safer and more efficient for both patients and medical teams.

 

Monogram Orthopaedics

 

 

Monogram Orthopaedics is a US-based startup that’s leading the way in patient-specific joint replacement through a combination of robotics, AI and 3D printing. Their custom-designed knee and hip implants provide a superior anatomical fit, improving longevity and reducing failure rates compared to traditional implants.

By leveraging machine learning and robotic assistance, Monogram aims to deliver more precise and personalised orthopaedic procedures, improving patient mobility and recovery. Their technology-driven approach is redefining modern joint replacement surgery.

 

Canary Medical

 

 

Canary Medical, a Canadian-based startup founded in 2017, is pioneering smart orthopaedic implants that use embedded sensors and AI to monitor patient recovery in real time.

Their Canturio Tibial Extension is the world’s first implant capable of collecting continuous data on movement and implant performance, allowing clinicians to detect complications early.

This revolutionary technology bridges the gap between digital health and orthopaedic surgery, offering a proactive approach to post-surgical care. Canary Medical is leading the charge in data-driven, connected healthcare solutions.

 

Abanza

 

 

Founded in 2008, Abanza is an orthopaedic biomaterials innovator, specialising in implant coatings and bone regeneration solutions. Their advanced hydroxyapatite coatings and bioactive materials improve implant integration, reduce infection risks and enhance bone healing.

By developing next-generation biocompatible surfaces, this Spanish startup is improving the longevity and safety of orthopaedic implants. With a focus on materials science and biotechnology, the company is playing a key role in advancing implant technology for more durable and effective orthopaedic solutions.